Loop L1 governs the DNA-binding specificity and order for RecA-catalyzed reactions in homologous recombination and DNA repair

In all organisms, RecA-family recombinases catalyze homologous joint formation in homologous genetic recombination, which is essential for genome stability and diversification. In homologous joint formation, ATP-bound RecA/Rad51-recombinases first bind single-stranded DNA at its primary site and the...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Shinohara, Takeshi, Ikawa, Shukuko, Iwasaki, Wakana, Hiraki, Toshiki, Hikima, Takaaki, Mikawa, Tsutomu, Arai, Naoto, Kamiya, Nobuo, Shibata, Takehiko
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Genome Integrity, Repair and Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333409/
https://ncbi.nlm.nih.gov/pubmed/25561575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1364
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