TET1 is controlled by pluripotency-associated factors in ESCs and downmodulated by PRC2 in differentiated cells and tissues

Ten-eleven translocation (Tet) genes encode for a family of hydroxymethylase enzymes involved in regulating DNA methylation dynamics. Tet1 is highly expressed in mouse embryonic stem cells (ESCs) where it plays a critical role the pluripotency maintenance. Tet1 is also involved in cell reprogramming...

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Enregistré dans:
Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Neri, Francesco, Incarnato, Danny, Krepelova, Anna, Dettori, Daniela, Rapelli, Stefania, Maldotti, Mara, Parlato, Caterina, Anselmi, Francesca, Galvagni, Federico, Oliviero, Salvatore
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2015
Sujets:
Gene regulation, Chromatin and Epigenetics
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538807/
https://ncbi.nlm.nih.gov/pubmed/25925565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv392
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