TET1 is controlled by pluripotency-associated factors in ESCs and downmodulated by PRC2 in differentiated cells and tissues

Ten-eleven translocation (Tet) genes encode for a family of hydroxymethylase enzymes involved in regulating DNA methylation dynamics. Tet1 is highly expressed in mouse embryonic stem cells (ESCs) where it plays a critical role the pluripotency maintenance. Tet1 is also involved in cell reprogramming...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Nucleic Acids Res
Glavni autori: Neri, Francesco, Incarnato, Danny, Krepelova, Anna, Dettori, Daniela, Rapelli, Stefania, Maldotti, Mara, Parlato, Caterina, Anselmi, Francesca, Galvagni, Federico, Oliviero, Salvatore
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2015
Teme:
Gene regulation, Chromatin and Epigenetics
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538807/
https://ncbi.nlm.nih.gov/pubmed/25925565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv392
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items