SOD1 aggregation in ALS mice shows simplistic test tube behavior

A longstanding challenge in studies of neurodegenerative disease has been that the pathologic protein aggregates in live tissue are not amenable to structural and kinetic analysis by conventional methods. The situation is put in focus by the current progress in demarcating protein aggregation in vit...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphovsmän: Lang, Lisa, Zetterström, Per, Brännström, Thomas, Marklund, Stefan L., Danielsson, Jens, Oliveberg, Mikael
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2015
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538623/
https://ncbi.nlm.nih.gov/pubmed/26221023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1503328112
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