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SOD1 aggregation in ALS mice shows simplistic test tube behavior

A longstanding challenge in studies of neurodegenerative disease has been that the pathologic protein aggregates in live tissue are not amenable to structural and kinetic analysis by conventional methods. The situation is put in focus by the current progress in demarcating protein aggregation in vit...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Lang, Lisa, Zetterström, Per, Brännström, Thomas, Marklund, Stefan L., Danielsson, Jens, Oliveberg, Mikael
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538623/
https://ncbi.nlm.nih.gov/pubmed/26221023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1503328112
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