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SOD1 aggregation in ALS mice shows simplistic test tube behavior

A longstanding challenge in studies of neurodegenerative disease has been that the pathologic protein aggregates in live tissue are not amenable to structural and kinetic analysis by conventional methods. The situation is put in focus by the current progress in demarcating protein aggregation in vit...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Lang, Lisa, Zetterström, Per, Brännström, Thomas, Marklund, Stefan L., Danielsson, Jens, Oliveberg, Mikael
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538623/
https://ncbi.nlm.nih.gov/pubmed/26221023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1503328112
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