A Drug-Disease Model Describing the Effect of Oseltamivir Neuraminidase Inhibition on Influenza Virus Progression

A population drug-disease model was developed to describe the time course of influenza virus with and without oseltamivir treatment and to investigate opportunities for antiviral combination therapy. Data included viral titers from 208 subjects, across 4 studies, receiving placebo and oseltamivir at...

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Kamal, Mohamed A., Gieschke, Ronald, Lemenuel-Diot, Annabelle, Beauchemin, Catherine A. A., Smith, Patrick F., Rayner, Craig R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2015
Matèries:
Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538552/
https://ncbi.nlm.nih.gov/pubmed/26100715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00069-15
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