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A Drug-Disease Model Describing the Effect of Oseltamivir Neuraminidase Inhibition on Influenza Virus Progression

A population drug-disease model was developed to describe the time course of influenza virus with and without oseltamivir treatment and to investigate opportunities for antiviral combination therapy. Data included viral titers from 208 subjects, across 4 studies, receiving placebo and oseltamivir at...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Kamal, Mohamed A., Gieschke, Ronald, Lemenuel-Diot, Annabelle, Beauchemin, Catherine A. A., Smith, Patrick F., Rayner, Craig R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538552/
https://ncbi.nlm.nih.gov/pubmed/26100715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00069-15
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