Neuraminidase Mutations Conferring Resistance to Oseltamivir in Influenza A(H7N9) Viruses

Human infections by avian influenza A(H7N9) virus entail substantial morbidity and mortality. Treatment of infected patients with the neuraminidase (NA) inhibitor oseltamivir was associated with emergence of viruses carrying NA substitutions. In the NA inhibition (NI) assay, R292K conferred highly r...

Full description

Saved in:
Bibliographic Details
Published in:J Virol
Main Authors: Marjuki, Henju, Mishin, Vasiliy P., Chesnokov, Anton P., De La Cruz, Juan A., Davis, Charles T., Villanueva, Julie M., Fry, Alicia M., Gubareva, Larisa V.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2015
Subjects:
Vaccines and Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442539/
https://ncbi.nlm.nih.gov/pubmed/25740997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03513-14
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items