Susceptibilities of Antiviral-Resistant Influenza Viruses to Novel Neuraminidase Inhibitors

The susceptibilities of five zanamivir-resistant and six oseltamivir-resistant influenza viruses were assessed against four neuraminidase (NA) inhibitors, including peramivir and A-315675, by a fluorometric NA activity inhibition assay. The enzyme activity of a majority of the variants was effective...

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Bibliographic Details
Main Authors: Mishin, Vasiliy P., Hayden, Frederick G., Gubareva, Larisa V.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
Subjects:
Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1280118/
https://ncbi.nlm.nih.gov/pubmed/16251290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.11.4515-4520.2005
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