Assessment of Pandemic and Seasonal Influenza A (H1N1) Virus Susceptibility to Neuraminidase Inhibitors in Three Enzyme Activity Inhibition Assays

The neuraminidase inhibitors (NAIs) zanamivir and oseltamivir are currently the only antiviral drugs effective for the treatment and prophylaxis of 2009 pandemic influenza A (H1N1) virus infections. The proven potential of these viruses to acquire NAI resistance during treatment emphasizes the need...

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Bibliographic Details
Main Authors: Nguyen, Ha T., Sheu, Tiffany G., Mishin, Vasiliy P., Klimov, Alexander I., Gubareva, Larisa V.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2010
Subjects:
Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2934949/
https://ncbi.nlm.nih.gov/pubmed/20585136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00581-10
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