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Neuraminidase Mutations Conferring Resistance to Oseltamivir in Influenza A(H7N9) Viruses
Human infections by avian influenza A(H7N9) virus entail substantial morbidity and mortality. Treatment of infected patients with the neuraminidase (NA) inhibitor oseltamivir was associated with emergence of viruses carrying NA substitutions. In the NA inhibition (NI) assay, R292K conferred highly r...
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| Vydáno v: | J Virol |
|---|---|
| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4442539/ https://ncbi.nlm.nih.gov/pubmed/25740997 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03513-14 |
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