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A Drug-Disease Model Describing the Effect of Oseltamivir Neuraminidase Inhibition on Influenza Virus Progression

A population drug-disease model was developed to describe the time course of influenza virus with and without oseltamivir treatment and to investigate opportunities for antiviral combination therapy. Data included viral titers from 208 subjects, across 4 studies, receiving placebo and oseltamivir at...

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Foilsithe in:Antimicrob Agents Chemother
Main Authors: Kamal, Mohamed A., Gieschke, Ronald, Lemenuel-Diot, Annabelle, Beauchemin, Catherine A. A., Smith, Patrick F., Rayner, Craig R.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538552/
https://ncbi.nlm.nih.gov/pubmed/26100715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00069-15
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