Population Pharmacokinetics of Oseltamivir: Pediatrics through Geriatrics

Oseltamivir is a potent inhibitor of influenza virus neuraminidase enzymes essential for viral replication. This study aimed to investigate the impact of covariates on pharmacokinetic (PK) variability of oseltamivir and its active metabolite form, oseltamivir carboxylate (OC). Dosing history, plasma...

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Main Authors: Kamal, Mohamed A., Van Wart, Scott A., Rayner, Craig R., Subramoney, Vishak, Reynolds, Daniel K., Bulik, Catharine C., Smith, Patrick F., Bhavnani, Sujata M., Ambrose, Paul G., Forrest, Alan
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2013
Teme:
Antiviral Agents
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719735/
https://ncbi.nlm.nih.gov/pubmed/23669384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02438-12
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