Population Pharmacokinetics of Oseltamivir: Pediatrics through Geriatrics

Oseltamivir is a potent inhibitor of influenza virus neuraminidase enzymes essential for viral replication. This study aimed to investigate the impact of covariates on pharmacokinetic (PK) variability of oseltamivir and its active metabolite form, oseltamivir carboxylate (OC). Dosing history, plasma...

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Detalhes bibliográficos
Main Authors: Kamal, Mohamed A., Van Wart, Scott A., Rayner, Craig R., Subramoney, Vishak, Reynolds, Daniel K., Bulik, Catharine C., Smith, Patrick F., Bhavnani, Sujata M., Ambrose, Paul G., Forrest, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719735/
https://ncbi.nlm.nih.gov/pubmed/23669384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02438-12
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