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A combination hydrogel microparticle-based vaccine prevents type 1 diabetes in non-obese diabetic mice
Targeted delivery of self-antigens to the immune system in a mode that stimulates a tolerance-inducing pathway has proven difficult. To address this hurdle, we developed a vaccine based-approach comprised of two synthetic controlled-release biomaterials, poly(lactide-co-glycolide; PLGA) microparticl...
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| Publicado en: | Sci Rep |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4538389/ https://ncbi.nlm.nih.gov/pubmed/26279095 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13155 |
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