Dual-Sized Microparticle System for Generating Suppressive Dendritic Cells Prevents and Reverses Type 1 Diabetes in the Nonobese Diabetic Mouse Model

[Image: see text] Antigen specificity is a primary goal in developing curative therapies for autoimmune disease. Dendritic cells (DCs), as the most effective antigen presenting cells in the body, represent a key target to mediate restoration of antigen-specific immune regulation. Here, we describe a...

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Vydáno v:ACS Biomater Sci Eng
Hlavní autoři: Lewis, Jamal S., Stewart, Joshua M., Marshall, Gregory P., Carstens, Matthew R., Zhang, Ying, Dolgova, Natalia V., Xia, Changqing, Brusko, Todd M., Wasserfall, Clive H., Clare-Salzler, Michael J., Atkinson, Mark A., Keselowsky, Benjamin G.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2019
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6518351/
https://ncbi.nlm.nih.gov/pubmed/31119191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsbiomaterials.9b00332
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