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IFN-γ-induced JAK/STAT, but not NF-κB, signaling pathway is insensitive to glucocorticoid in airway epithelial cells

Although the majority of patients with asthma are well controlled by inhaled glucocorticoids (GCs), patients with severe asthma are poorly responsive to GCs. This latter group is responsible for a disproportionate share of health care costs associated with asthma. Recent studies in immune cells have...

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Detaylı Bibliyografya
Yayımlandı:Am J Physiol Lung Cell Mol Physiol
Asıl Yazarlar: O'Connell, Danielle, Bouazza, Belaid, Kokalari, Blerina, Amrani, Yassine, Khatib, Alaa, Ganther, John David, Tliba, Omar
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538237/
https://ncbi.nlm.nih.gov/pubmed/26092996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00099.2015
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