IFN-γ-induced JAK/STAT, but not NF-κB, signaling pathway is insensitive to glucocorticoid in airway epithelial cells

Although the majority of patients with asthma are well controlled by inhaled glucocorticoids (GCs), patients with severe asthma are poorly responsive to GCs. This latter group is responsible for a disproportionate share of health care costs associated with asthma. Recent studies in immune cells have...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: O'Connell, Danielle, Bouazza, Belaid, Kokalari, Blerina, Amrani, Yassine, Khatib, Alaa, Ganther, John David, Tliba, Omar
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
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Call for Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538237/
https://ncbi.nlm.nih.gov/pubmed/26092996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00099.2015
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