Basal p38 Mitogen-Activated Protein Kinase Regulates Unliganded Glucocorticoid Receptor Function in Airway Smooth Muscle Cells

Like many steroid receptors, the glucocorticoid (GC) receptor (GR) is a phosphoprotein. Although there are multiple phosphorylation sites critical for GR transcriptional activity (i.e., serine [S]203, S211, and S226), their respective role in driving GR functions is highly cell specific. We have rec...

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Detalhes bibliográficos
Main Authors: Bouazza, Belaid, Debba-Pavard, Manel, Amrani, Yassine, Isaacs, Lauren, O’Connell, Danielle, Ahamed, Sara, Formella, Danielle, Tliba, Omar
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2014
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930943/
https://ncbi.nlm.nih.gov/pubmed/24024586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2012-0522OC
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