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Important lessons learned from studies on the pharmacology of glucocorticoids in human airway smooth muscle cells: too much of a good thing may be a problem

Glucocorticoids (GCs) are the treatment of choice for chronic inflammatory diseases such as asthma. Despite proven effective anti-inflammatory and immunosuppressive effects, long-term and/or systemic use of GCs can potentially induce adverse effects. Strikingly, some recent experimental evidence sug...

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Detalhes bibliográficos
Publicado no:Pharmacol Ther
Main Authors: Amrani, Yassine, Panettieri, Reynold A., Ramos-Ramírez, Patricia, Schaafsma, Dedmer, Kaczmarek, Klaudia, Tliba, Omar
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7434707/
https://ncbi.nlm.nih.gov/pubmed/32473159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2020.107589
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