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Cytokines Alter Glucocorticoid Receptor Phosphorylation in Airway Cells: Role of Phosphatases
Corticosteroid insensitivity (CSI) represents a profound challenge in managing patients with asthma. We recently demonstrated that short exposure of airway smooth muscle cells (ASMCs) to proasthmatic cytokines drastically reduced their responsiveness to glucocorticoids (GCs), an effect that was part...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Thoracic Society
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3488623/ https://ncbi.nlm.nih.gov/pubmed/22592921 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2011-0364OC |
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