Cytokines Alter Glucocorticoid Receptor Phosphorylation in Airway Cells: Role of Phosphatases

Corticosteroid insensitivity (CSI) represents a profound challenge in managing patients with asthma. We recently demonstrated that short exposure of airway smooth muscle cells (ASMCs) to proasthmatic cytokines drastically reduced their responsiveness to glucocorticoids (GCs), an effect that was part...

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Detalhes bibliográficos
Main Authors: Bouazza, Belaid, Krytska, Kateryna, Debba-Pavard, Manel, Amrani, Yassine, Honkanen, Richard E., Tran, Jennifer, Tliba, Omar
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488623/
https://ncbi.nlm.nih.gov/pubmed/22592921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2011-0364OC
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