Brain-Specific Superoxide Dismutase 2 Deficiency Causes Perinatal Death with Spongiform Encephalopathy in Mice

Oxidative stress is believed to greatly contribute to the pathogenesis of various diseases, including neurodegeneration. Impairment of mitochondrial energy production and increased mitochondrial oxidative damage are considered early pathological events that lead to neurodegeneration. Manganese super...

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Vydáno v:Oxid Med Cell Longev
Hlavní autoři: Izuo, Naotaka, Nojiri, Hidetoshi, Uchiyama, Satoshi, Noda, Yoshihiro, Kawakami, Satoru, Kojima, Shuji, Sasaki, Toru, Shirasawa, Takuji, Shimizu, Takahiko
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4537744/
https://ncbi.nlm.nih.gov/pubmed/26301039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/238914
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