Brain-Specific Superoxide Dismutase 2 Deficiency Causes Perinatal Death with Spongiform Encephalopathy in Mice

Oxidative stress is believed to greatly contribute to the pathogenesis of various diseases, including neurodegeneration. Impairment of mitochondrial energy production and increased mitochondrial oxidative damage are considered early pathological events that lead to neurodegeneration. Manganese super...

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Veröffentlicht in:Oxid Med Cell Longev
Hauptverfasser: Izuo, Naotaka, Nojiri, Hidetoshi, Uchiyama, Satoshi, Noda, Yoshihiro, Kawakami, Satoru, Kojima, Shuji, Sasaki, Toru, Shirasawa, Takuji, Shimizu, Takahiko
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4537744/
https://ncbi.nlm.nih.gov/pubmed/26301039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/238914
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