Brain-Specific Superoxide Dismutase 2 Deficiency Causes Perinatal Death with Spongiform Encephalopathy in Mice

Oxidative stress is believed to greatly contribute to the pathogenesis of various diseases, including neurodegeneration. Impairment of mitochondrial energy production and increased mitochondrial oxidative damage are considered early pathological events that lead to neurodegeneration. Manganese super...

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Опубликовано в: :Oxid Med Cell Longev
Главные авторы: Izuo, Naotaka, Nojiri, Hidetoshi, Uchiyama, Satoshi, Noda, Yoshihiro, Kawakami, Satoru, Kojima, Shuji, Sasaki, Toru, Shirasawa, Takuji, Shimizu, Takahiko
Формат: Artigo
Язык:Inglês
Опубликовано: Hindawi Publishing Corporation 2015
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4537744/
https://ncbi.nlm.nih.gov/pubmed/26301039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/238914
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