Brain-Specific Superoxide Dismutase 2 Deficiency Causes Perinatal Death with Spongiform Encephalopathy in Mice

Oxidative stress is believed to greatly contribute to the pathogenesis of various diseases, including neurodegeneration. Impairment of mitochondrial energy production and increased mitochondrial oxidative damage are considered early pathological events that lead to neurodegeneration. Manganese super...

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Detalles Bibliográficos
Publicado en:Oxid Med Cell Longev
Main Authors: Izuo, Naotaka, Nojiri, Hidetoshi, Uchiyama, Satoshi, Noda, Yoshihiro, Kawakami, Satoru, Kojima, Shuji, Sasaki, Toru, Shirasawa, Takuji, Shimizu, Takahiko
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 2015
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4537744/
https://ncbi.nlm.nih.gov/pubmed/26301039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/238914
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