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High-Throughput Minigenome System for Identifying Small-Molecule Inhibitors of Ebola Virus Replication

[Image: see text] Ebola virus (EBOV), a member of the family Filoviridae, is a nonsegmented negative-sense RNA virus that causes severe, often lethal, disease in humans. EBOV RNA synthesis is carried out by a complex that includes several viral proteins. The function of this machinery is essential f...

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Detalhes bibliográficos
Publicado no:ACS Infect Dis
Main Authors: Edwards, Megan R., Pietzsch, Colette, Vausselin, Thibaut, Shaw, Megan L., Bukreyev, Alexander, Basler, Christopher F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4537067/
https://ncbi.nlm.nih.gov/pubmed/26284260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.5b00053
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