An RNAi-based high-throughput screening assay to identify small molecule inhibitors of hepatitis B virus replication

Persistent or chronic infection with the hepatitis B virus (HBV) represents one of the most common viral diseases in humans. The hepatitis B virus deploys the hepatitis B virus X protein (HBx) as a suppressor of host defenses consisting of RNAi-based silencing of viral genes. Because of its critical...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Ghosh, Subhanita, Kaushik, Abhinav, Khurana, Sachin, Varshney, Aditi, Singh, Avishek Kumar, Dahiya, Pradeep, Thakur, Jitendra K., Sarin, Shiv Kumar, Gupta, Dinesh, Malhotra, Pawan, Mukherjee, Sunil K., Bhatnagar, Raj K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5535032/
https://ncbi.nlm.nih.gov/pubmed/28584057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.775155
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