Blocking TWEAK-Fn14 interaction inhibits hematopoietic stem cell transplantation-induced intestinal cell death and reduces GVHD

Inhibition of the tumor necrosis factor (TNF)-like weak inducer of apoptosis (TWEAK)/fibroblast growth factor-inducible 14 (Fn14) system reduces intestinal cell death and disease development in several models of colitis. In view of the crucial role of TNF and intestinal cell death in graft-versus-ho...

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Bibliographic Details
Published in:Blood
Main Authors: Chopra, Martin, Brandl, Andreas, Siegmund, Daniela, Mottok, Anja, Schäfer, Viktoria, Biehl, Marlene, Kraus, Sabrina, Bäuerlein, Carina A., Ritz, Miriam, Mattenheimer, Katharina, Schwinn, Stefanie, Seher, Axel, Grabinger, Thomas, Einsele, Hermann, Rosenwald, Andreas, Brunner, Thomas, Beilhack, Andreas, Wajant, Harald
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2015
Subjects:
Plenary Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4536890/
https://ncbi.nlm.nih.gov/pubmed/26012567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-01-620583
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