Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain.
Nonsteroidal antiinflammatory drugs (NSAIDs) are widely used for the treatment of inflammatory diseases, but significant side effects such as gastrointestinal erosion and renal damage limit their use. NSAIDs inhibit the enzyme cyclooxygenase (COX), which catalyzes the conversion of arachidonic acid...
Guardat en:
| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1994
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45366/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7991575/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.25.12013 |
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