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Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain.

Nonsteroidal antiinflammatory drugs (NSAIDs) are widely used for the treatment of inflammatory diseases, but significant side effects such as gastrointestinal erosion and renal damage limit their use. NSAIDs inhibit the enzyme cyclooxygenase (COX), which catalyzes the conversion of arachidonic acid...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Seibert, K, Zhang, Y, Leahy, K, Hauser, S, Masferrer, J, Perkins, W, Lee, L, Isakson, P
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1994
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC45366/
https://ncbi.nlm.nih.gov/pubmed/7991575
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