Cyclooxygenase-2 inhibition prevents delayed death of CA1 hippocampal neurons following global ischemia

The inducible isoform of the enzyme cyclooxygenase-2 (COX2) is an immediate early gene induced by synaptic activity in the brain. COX2 activity is an important mediator of inflammation, but it is not known whether COX2 activity is pathogenic in brain. To study the role of COX2 activity in ischemic i...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Nakayama, Masaki, Uchimura, Koichi, Zhu, Raymond Li, Nagayama, Tetsuya, Rose, Marie E., Stetler, R. Anne, Isakson, Peter C., Chen, Jun, Graham, Steven H.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1998
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC28002/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9724811/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.18.10954
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