Cyclooxygenase-2 inhibition prevents delayed death of CA1 hippocampal neurons following global ischemia

The inducible isoform of the enzyme cyclooxygenase-2 (COX2) is an immediate early gene induced by synaptic activity in the brain. COX2 activity is an important mediator of inflammation, but it is not known whether COX2 activity is pathogenic in brain. To study the role of COX2 activity in ischemic i...

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הוצא לאור ב:	Proc Natl Acad Sci U S A
Principais autores:	Nakayama, Masaki, Uchimura, Koichi, Zhu, Raymond Li, Nagayama, Tetsuya, Rose, Marie E., Stetler, R. Anne, Isakson, Peter C., Chen, Jun, Graham, Steven H.
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	National Academy of Sciences 1998
נושאים:	Biological Sciences
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC28002/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9724811/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.18.10954
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