Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain.

Nonsteroidal antiinflammatory drugs (NSAIDs) are widely used for the treatment of inflammatory diseases, but significant side effects such as gastrointestinal erosion and renal damage limit their use. NSAIDs inhibit the enzyme cyclooxygenase (COX), which catalyzes the conversion of arachidonic acid...

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Bibliografski detalji

Izdano u:	Proc Natl Acad Sci U S A
Glavni autori:	Seibert, K, Zhang, Y, Leahy, K, Hauser, S, Masferrer, J, Perkins, W, Lee, L, Isakson, P
Format:	Artigo
Jezik:	Inglês
Izdano:	National Academy of Sciences 1994
Teme:	Research Article
Online pristup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45366/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7991575/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.25.12013
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