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Xanthohumol Improves Diet-induced Obesity and Fatty Liver by Suppressing Sterol Regulatory Element-binding Protein (SREBP) Activation

Sterol regulatory element-binding proteins (SREBPs) are key transcription factors that stimulate the expression of genes involved in fatty acid and cholesterol biosynthesis. Here, we demonstrate that a prenylated flavonoid in hops, xanthohumol (XN), is a novel SREBP inactivator that reduces the de n...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Miyata, Shingo, Inoue, Jun, Shimizu, Makoto, Sato, Ryuichiro
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4536460/
https://ncbi.nlm.nih.gov/pubmed/26140926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.656975
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