Pediatric severe asthma with fungal sensitization is mediated by steroid-resistant IL-33

BACKGROUND: The mechanism underlying severe asthma with fungal sensitization (SAFS) is unknown. IL-33 is important in fungus-induced asthma exacerbations, but its role in fungal sensitization is unexplored. OBJECTIVE: We sought to determine whether fungal sensitization in children with severe therap...

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Detalhes bibliográficos
Publicado no:J Allergy Clin Immunol
Main Authors: Castanhinha, Susana, Sherburn, Rebekah, Walker, Simone, Gupta, Atul, Bossley, Cara J., Buckley, James, Ullmann, Nicola, Grychtol, Ruth, Campbell, Gaynor, Maglione, Marco, Koo, Sergio, Fleming, Louise, Gregory, Lisa, Snelgrove, Robert J., Bush, Andrew, Lloyd, Clare M., Saglani, Sejal
Formato: Artigo
Idioma:Inglês
Publicado em: Mosby 2015
Assuntos:
Asthma and Lower Airway Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534777/
https://ncbi.nlm.nih.gov/pubmed/25746970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2015.01.016
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