Intraepithelial neutrophils in pediatric severe asthma are associated with better lung function

BACKGROUND: Neutrophils and IL-17A have been linked mechanistically in models of allergic airways disease and have been associated with asthma severity. However, their role in pediatric asthma is unknown. OBJECTIVES: We sought to investigate the role of neutrophils and the IL-17A pathway in mediatin...

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Detalhes bibliográficos
Publicado no:J Allergy Clin Immunol
Main Authors: Andersson, Cecilia K., Adams, Alexandra, Nagakumar, Prasad, Bossley, Cara, Gupta, Atul, De Vries, Daphne, Adnan, Afiqah, Bush, Andrew, Saglani, Sejal, Lloyd, Clare M.
Formato: Artigo
Idioma:Inglês
Publicado em: Mosby 2017
Assuntos:
Asthma and Lower Airway Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5457125/
https://ncbi.nlm.nih.gov/pubmed/27746241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2016.09.022
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