Interleukin-33 promotes airway remodelling in paediatric severe steroid resistant asthma

BACKGROUND: Th2 cytokines are not responsible for the on-going symptoms and pathology in children with severe therapy resistant asthma (STRA). Interleukin (IL)-33 induces airway hyperresponsiveness (AHR), but its role in airway remodelling and steroid resistance is unknown. OBJECTIVE: To investigate...

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Vydáno v:J Allergy Clin Immunol
Hlavní autoři: Saglani, Sejal, Lui, Stephen, Ullmann, Nicola, Campbell, Gaynor, Sherburn, Rebekah, Mathie, Sara, Denney, Laura, Bossley, Cara J, Oates, Timothy, Walker, Simone, Bush, Andrew, Lloyd, Clare M
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218948/
https://ncbi.nlm.nih.gov/pubmed/23759184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2013.04.012
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