Preserved Expression of mRNA Coding von Willebrand Factor–Cleaving Protease ADAMTS13 by Selenite and Activated Protein C

In sepsis, the severity-dependent decrease of von Willebrand factor (VWF)–inactivating protease, a disintegrin and metalloproteinase with thrombospondin motifs 13 (ADAMTS13), results in platelet aggregation and consumption, leading to sepsis-associated thrombotic microangiopathy (TMA) and organ fail...

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Publicado no:Mol Med
Main Authors: Ekaney, Michael L, Bockmeyer, Clemens L, Sossdorf, Maik, Reuken, Philipp A, Conradi, Florian, Schuerholz, Tobias, Blaess, Markus F, Friedman, Scott L, Lösche, Wolfgang, Bauer, Michael, Claus, Ralf A
Formato: Artigo
Idioma:Inglês
Publicado em: ScholarOne 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534472/
https://ncbi.nlm.nih.gov/pubmed/25860876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2014.00202
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