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Unraveling the scissile bond: how ADAMTS13 recognizes and cleaves von Willebrand factor
von Willebrand factor (VWF) is a large adhesive glycoprotein with established functions in hemostasis. It serves as a carrier for factor VIII and acts as a vascular damage sensor by attracting platelets to sites of vessel injury. VWF size is important for this latter function, with larger multimers...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3179391/ https://ncbi.nlm.nih.gov/pubmed/21715306 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-02-306597 |
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