Synthesis and Evaluation of Chloramphenicol Homodimers: Molecular Target, Antimicrobial Activity, and Toxicity against Human Cells

As fight against antibiotic resistance must be strengthened, improving old drugs that have fallen in reduced clinical use because of toxic side effects and/or frequently reported resistance, like chloramphenicol (CAM), is of special interest. Chloramphenicol (CAM), a prototypical wide-spectrum antib...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Kostopoulou, Ourania N., Magoulas, George E., Papadopoulos, Georgios E., Mouzaki, Athanasia, Dinos, George P., Papaioannou, Dionissios, Kalpaxis, Dimitrios L.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4533973/
https://ncbi.nlm.nih.gov/pubmed/26267355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134526
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