Chloramphenicol Derivatives as Antibacterial and Anticancer Agents: Historic Problems and Current Solutions

Chloramphenicol (CAM) is the D-threo isomer of a small molecule, consisting of a p-nitrobenzene ring connected to a dichloroacetyl tail through a 2-amino-1,3-propanediol moiety. CAM displays a broad-spectrum bacteriostatic activity by specifically inhibiting the bacterial protein synthesis. In certa...

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Enregistré dans:
Détails bibliographiques
Publié dans:Antibiotics (Basel)
Auteurs principaux: Dinos, George P., Athanassopoulos, Constantinos M., Missiri, Dionissia A., Giannopoulou, Panagiota C., Vlachogiannis, Ioannis A., Papadopoulos, Georgios E., Papaioannou, Dionissios, Kalpaxis, Dimitrios L.
Format: Artigo
Langue:Inglês
Publié: MDPI 2016
Sujets:
Review
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4929435/
https://ncbi.nlm.nih.gov/pubmed/27271676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antibiotics5020020
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