Synthesis and Evaluation of Chloramphenicol Homodimers: Molecular Target, Antimicrobial Activity, and Toxicity against Human Cells

As fight against antibiotic resistance must be strengthened, improving old drugs that have fallen in reduced clinical use because of toxic side effects and/or frequently reported resistance, like chloramphenicol (CAM), is of special interest. Chloramphenicol (CAM), a prototypical wide-spectrum antib...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kostopoulou, Ourania N., Magoulas, George E., Papadopoulos, Georgios E., Mouzaki, Athanasia, Dinos, George P., Papaioannou, Dionissios, Kalpaxis, Dimitrios L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4533973/
https://ncbi.nlm.nih.gov/pubmed/26267355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134526
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