Splenectomy Protects against Sepsis Lethality and Reduces Serum HMGB1 Levels()

High mobility group box 1 (HMGB1) is a critical mediator of lethal sepsis. Previously, we showed that apoptotic cells can activate macrophages to release HMGB1. During sepsis, apoptosis occurs primarily in lymphoid organs, including the spleen and thymus. Currently, it is unclear whether this accele...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Immunol
Egile Nagusiak: Huston, Jared M., Wang, Haichao, Ochani, Mahendar, Ochani, Kanta, Rosas-Ballina, Mauricio, Gallowitsch-Puerta, Margot, Ashok, Mala, Yang, Lihong, Tracey, Kevin J., Yang, Huan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4533852/
https://ncbi.nlm.nih.gov/pubmed/18714026
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