Splenectomy Protects against Sepsis Lethality and Reduces Serum HMGB1 Levels()

High mobility group box 1 (HMGB1) is a critical mediator of lethal sepsis. Previously, we showed that apoptotic cells can activate macrophages to release HMGB1. During sepsis, apoptosis occurs primarily in lymphoid organs, including the spleen and thymus. Currently, it is unclear whether this accele...

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Bibliografske podrobnosti
izdano v:J Immunol
Main Authors: Huston, Jared M., Wang, Haichao, Ochani, Mahendar, Ochani, Kanta, Rosas-Ballina, Mauricio, Gallowitsch-Puerta, Margot, Ashok, Mala, Yang, Lihong, Tracey, Kevin J., Yang, Huan
Format: Artigo
Jezik:Inglês
Izdano: 2008
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4533852/
https://ncbi.nlm.nih.gov/pubmed/18714026
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