The Novel Cyclophilin Inhibitor CPI-431-32 Concurrently Blocks HCV and HIV-1 Infections via a Similar Mechanism of Action

HCV-related liver disease is the main cause of morbidity and mortality of HCV/HIV-1 co-infected patients. Despite the recent advent of anti-HCV direct acting antivirals (DAAs), the treatment of HCV/HIV-1 co-infected patients remains a challenge, as these patients are refractory to most therapies and...

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Pubblicato in:PLoS One
Autori principali: Gallay, Philippe A., Bobardt, Michael D., Chatterji, Udayan, Trepanier, Daniel J., Ure, Daren, Ordonez, Cosme, Foster, Robert
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4532424/
https://ncbi.nlm.nih.gov/pubmed/26263487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134707
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