Wordt geladen...
Both Cyclophilin Inhibitors and Direct-Acting Antivirals Prevent PKR Activation in HCV-Infected Cells
We and others demonstrated that the contact between NS5A and the host factor CypA is critical for HCV replication. CypI, by disrupting NS5A-CypA complexes, block HCV replication both in vitro and in patients. Since NS5A also binds to PKR, a central component of the IFN response, we investigated the...
Bewaard in:
| Hoofdauteurs: | , , , , |
|---|---|
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Bentham Open
2014
|
| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4009744/ https://ncbi.nlm.nih.gov/pubmed/24799968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1874357901408010001 |
| Tags: |
Voeg label toe
Geen labels, Wees de eerste die dit record labelt!
|