Extracellular Adenosine Formation by Ecto-5’-Nucleotidase (CD73) Is No Essential Trigger for Early Phase Ischemic Preconditioning

BACKGROUND: Adenosine is a powerful trigger for ischemic preconditioning (IPC). Myocardial ischemia induces intracellular and extracellular ATP degradation to adenosine, which then activates adenosine receptors and elicits cardioprotection. Conventionally extracellular adenosine formation by ecto-5’...

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Publicado en:PLoS One
Autores principales: Wolff, Georg, Truse, Richard, Decking, Ulrich
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4532361/
https://ncbi.nlm.nih.gov/pubmed/26261991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135086
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