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Ecto-5′-Nucleotidase (CD73) Inhibits Nociception by Hydrolyzing AMP to Adenosine in Nociceptive Circuits

Ecto-5′-nucleotidase (NT5E, CD73) is a membrane-anchored protein that hydrolyzes extracellular adenosine 5′-monophosphate (AMP) to adenosine in diverse tissues but has not been directly studied in nociceptive neurons. We found that NT5E was located on peptidergic and nonpeptidergic nociceptive neuro...

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Detaylı Bibliyografya
Asıl Yazarlar: Sowa, Nathaniel A., Taylor-Blake, Bonnie, Zylka, Mark J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Society for Neuroscience 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826808/
https://ncbi.nlm.nih.gov/pubmed/20147550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5324-09.2010
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