Tissue-resident ecto-5’ nucleotidase (CD73) regulates leukocyte trafficking in the ischemic brain

Ectoenzymes expressed on the surface of vascular cells and leukocytes modulate the ambient nucleotide milieu. CD73 is an ecto-5’ nucleotidase that catalyzes the terminal phosphohydrolysis of AMP and resides in the brain on glial cells, cells of the choroid plexus, and leukocytes. Though CD73 tighten...

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Hauptverfasser: Petrovic-Djergovic, Danica, Hyman, Matthew C., Ray, Jessica J., Bouis, Diane, Visovatti, Scott H., Hayasaki, Takanori, Pinsky, David J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3644975/
https://ncbi.nlm.nih.gov/pubmed/22291183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003671
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