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Ecto-5′ nucleotidase (CD73)-mediated adenosine generation and signaling in murine cardiac allograft vasculopathy

Ecto-5′-nucleotidase (CD73) catalyzes the terminal phosphohydrolysis of 5′-adenosine monophosphate, and is widely expressed on endothelial cells where it regulates barrier function. As it is also expressed on lymphocytes, we hypothesized that it modulates vascular immune regulation under homeostatic...

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Detalhes bibliográficos
Main Authors: Hasegawa, Tomomi, Bouïs, Diane, Liao, Hui, Visovatti, Scott H., Pinsky, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3644954/
https://ncbi.nlm.nih.gov/pubmed/19008478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.108.180059
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