Tracking the genomic evolution of esophageal adenocarcinoma through neoadjuvant chemotherapy

Esophageal adenocarcinomas (EACs) are associated with dismal prognosis. Deciphering the evolutionary histories of this disease may shed light on therapeutically tractable targets and reveal dynamic mutational processes during the disease course and following neoadjuvant chemotherapy (NAC). We exome...

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Gepubliceerd in:Cancer Discov
Hoofdauteurs: Murugaesu, Nirupa, Wilson, Gareth A, Birkbak, Nicolai J, Watkins, Thomas, McGranahan, Nicholas, Kumar, Sacheen, Abbassi-Ghadi, Nima, Salm, Max, Mitter, Richard, Horswell, Stuart, Rowan, Andrew, Phillimore, Benjamin, Biggs, Jennifer, Begum, Sharmin, Matthews, Nik, Hochhauser, Daniel, Hanna, George B, Swanton, Charles
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4529488/
https://ncbi.nlm.nih.gov/pubmed/26003801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-15-0412
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