Tracking the genomic evolution of esophageal adenocarcinoma through neoadjuvant chemotherapy

Esophageal adenocarcinomas (EACs) are associated with dismal prognosis. Deciphering the evolutionary histories of this disease may shed light on therapeutically tractable targets and reveal dynamic mutational processes during the disease course and following neoadjuvant chemotherapy (NAC). We exome...

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Bibliografiske detaljer
Udgivet i:Cancer Discov
Main Authors: Murugaesu, Nirupa, Wilson, Gareth A, Birkbak, Nicolai J, Watkins, Thomas, McGranahan, Nicholas, Kumar, Sacheen, Abbassi-Ghadi, Nima, Salm, Max, Mitter, Richard, Horswell, Stuart, Rowan, Andrew, Phillimore, Benjamin, Biggs, Jennifer, Begum, Sharmin, Matthews, Nik, Hochhauser, Daniel, Hanna, George B, Swanton, Charles
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4529488/
https://ncbi.nlm.nih.gov/pubmed/26003801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-15-0412
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