Tracking the genomic evolution of esophageal adenocarcinoma through neoadjuvant chemotherapy

Esophageal adenocarcinomas (EACs) are associated with dismal prognosis. Deciphering the evolutionary histories of this disease may shed light on therapeutically tractable targets and reveal dynamic mutational processes during the disease course and following neoadjuvant chemotherapy (NAC). We exome...

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Veröffentlicht in:Cancer Discov
Hauptverfasser: Murugaesu, Nirupa, Wilson, Gareth A, Birkbak, Nicolai J, Watkins, Thomas, McGranahan, Nicholas, Kumar, Sacheen, Abbassi-Ghadi, Nima, Salm, Max, Mitter, Richard, Horswell, Stuart, Rowan, Andrew, Phillimore, Benjamin, Biggs, Jennifer, Begum, Sharmin, Matthews, Nik, Hochhauser, Daniel, Hanna, George B, Swanton, Charles
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4529488/
https://ncbi.nlm.nih.gov/pubmed/26003801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-15-0412
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