Tracking the genomic evolution of esophageal adenocarcinoma through neoadjuvant chemotherapy

Esophageal adenocarcinomas (EACs) are associated with dismal prognosis. Deciphering the evolutionary histories of this disease may shed light on therapeutically tractable targets and reveal dynamic mutational processes during the disease course and following neoadjuvant chemotherapy (NAC). We exome...

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Foilsithe in:Cancer Discov
Main Authors: Murugaesu, Nirupa, Wilson, Gareth A, Birkbak, Nicolai J, Watkins, Thomas, McGranahan, Nicholas, Kumar, Sacheen, Abbassi-Ghadi, Nima, Salm, Max, Mitter, Richard, Horswell, Stuart, Rowan, Andrew, Phillimore, Benjamin, Biggs, Jennifer, Begum, Sharmin, Matthews, Nik, Hochhauser, Daniel, Hanna, George B, Swanton, Charles
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4529488/
https://ncbi.nlm.nih.gov/pubmed/26003801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-15-0412
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